Advertising works if you have enough money to cause a permanent impression on the mind of people you are after. Subliminal advertising was proven years ago to reach 25% of the audience and cause a reaction.
If you take these truths and set up a advertising campaign of 10,000,000 one second TV and Radio slots are purchased with simple adds running like: DEMOCRATES ARE DUMB, DEMOCRATES HATE AMERICA, DEMOCRATES FEAR THE CONSTITUTION, DEMOCRATE UNAMERICAN, you can turn DEMOCRATE into a dirty word in 6 months.
There has to be enough money involved to get the Media to go along with the 1 second slots, maybe $100,000,000.. You can do the same with republican, no bias intended.